Malignant Hyperthermia (MH) is a life-threatening disorder affecting 1 in every 2,000 - 3,000 people. This primarily hereditary condition is considered a, "pharmacogenetic disorder of the skeletal muscle." In layman's terms, having MH means you are susceptible to having an MH crisis. According to the Malignant Hyperthermia Association of the United States, "The general signs of the MH crisis include increased heart rate, greatly increased body metabolism, muscle rigidity and/or fever that may exceed 110 degrees F along with muscle breakdown, derangements of body chemicals and increased acide content in the blood. Severe complications can include cardiac arrest, brain damage, internal bleeding or failure of other body systems. Thus, death, primarily due to a secondary cardiovascular collapse, can result."